Grant McClelland index MacMaster
Muscle Remodeling    
Muscle Remodeling  
This research focuses on muscle plasticity in response to environmental and energetic stress and how this impacts on whole-animal performance. For this purpose we have developed the adult zebrafish as a model system to investigate molecular and biochemical aspects of vertebrate skeletal muscle and heart remodelling.

Sample publications:

McClelland, G.B. (2012) Muscle Remodeling and the Exercise Physiology of Fish. Exerc. Sport Sci. Rev. 40(3):165-173.

McClelland, G.B., and Scott, G.R. (2013) Muscle Plasticity. In: Evans, DH, Claiborne, J.B., and Currie, S (eds.). The Physiology of Fishes, 4th ed. CRC press, Baton Raton, Fl./em>

Le Moine, C.M.R., Craig, P.M., Dhekney, K., Kim, J.J., and McClelland, G.B. (2010) Temporal and spatial patterns of gene expression in skeletal muscles in response to swim training in adult zebrafish (Danio rerio). J. Comp. Physiol. B. 180(1):151-60.

McClelland, G.B.*, Craig, P.M., Dhekney, K and Dipardo, S. (2006) Temperature- and exercise-induced gene expression and metabolic enzyme changes in skeletal muscle of adult zebrafish (Danio rerio). J. Physiol. (London), 577(2):739-751.

Schippers, M.-P., Dukas, R., and McClelland, G.B. (2010) Lifetime changes in flight metabolic rate and muscle biochemistry of honeybees, Apis mellifera. J. Comp. Physiol. B. 180(1):45-55.
Research in the McClelland Lab is currently being funded by the National Sciences and Engineering Council (NSERC), PREA and a CFI New Opportunities Grant.  
Canada Foundation for Innovation  
Grant B. McClelland - McMaster University - Department of Biology - 1280 Main St. West Hamilton, ON L8S 4K1 Canada 
Office: 905.525.9140 x24266 - Lab: 905.525.9140 x23170 - Fax: 905.522.6066 | Grant can be e-mailed at grantm [at] mcmaster [dot] ca